The HapMap Project
The International HapMap Project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States.
The initial objective of the Project is to genotype one informative SNP approximately
every 5 kb throughout the human genome. Genotyping will be done in populations with ancestry from Nigeria, Europe, and China/Japan.
The goal is to determine
the common patterns of human DNA sequence variation (haplotypes) and to make this information freely available in the public domain. The information will
facilitate discovery of sequence variants that affect common disease and pharmaceutical response. Constructing the human haplotype map is a significant step
towards
personalized medicine.
Phase I of the HapMap Project
Parts of the genome were assigned to various investigators. Chromosome 7p (1.9 % of the genome) has been assigned to
Dr. Pui-Yan Kwok,
University of California, San Francisco,
and he has given a contract for half of the work to Dr. Ray Miller, Washington University, St. Louis. Both groups use the
FP-TDI genotyping technology invented by Dr. Kwok and colleagues.
Allele frequencies and actual genotypes are freely available at the HapMap website.
You can also view our
SNP genotyping results
for chromosome 7p.
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