About the Washington University SNP Research Facility
Our laboratory is headed by Dr. Raymond D. Miller, and located in the Genetics Department of Washington University School of Medicine in St. Louis, Missouri.
Our sister laboratory, headed by Pui Kwok, is located at the University of California - San Francisco.
Areas of Research
The majority of our research is related to single-nucleotide polymorphisms (SNPs).
We served as a genotyping center for the first phase of the International HapMap Project, a collaborative effort whose aim is to develop a high-density haplotype map of the human
genome. Currently, we are heading the NIH-funded effort to construct a
genetic map
for model organism Caenorhabditis briggsae.
See the research projects for details on our work.
SNP Genotyping and Other Core Services
We offer a variety of
core services
to investigators at Washington University and elsewhere. Our main service is high-throughput genotyping, for which we use
FP-TDI, a flexible and high-throughput platform
that was developed in our laboratory. We also assist researchers who need:
SNP selection in candidate genes for association studies
DNA quantification using pico green analysis
Assay design for genotyping or targeted DNA resequencing
SNP discovery in humans and model organisms
Scientific writing for grant proposals and publications
Please contact us to discuss how we might help with your genotyping project or association study.
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