Bio-informatics at the SNP Research Facility
Bio-informatics research and development plays two key roles: first, to develop and maintain a high-throughput Laboratory Information Management
System (LIMS), and second, to meet specific informatic needs of laboratory research projects.
The Informatics Team
| Dan Koboldt |
Bio-informatics efforts are led by Dan Koboldt, who joined the laboratory in 2003. |
| Research Blog |
Visit our lab's blog page for research updates and perspectives. |
Areas of Research
| SNP discovery |
We have used and evaluated several approaches to SNP discovery. |
| Assay Design |
Learn about our software that selects ideal primers for genotyping and resequencing. |
| Primer Site SNPs |
We have made extensive studies of the effect of SNPs in primer sites. |
| Genome Annotation |
In collaboration with UCSC, we annotate SNP loci in the human genome assembly. |
| Genetic Mapping |
Informatics played a key role in our construction of a genetic map for C. briggsae. |
LIMS Development
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LIMS Abstract
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A presentation of the high-throughput data pipeline that we built for SNP genotyping. Poster by Koboldt, Miller, and Kwok (RECOMB 2004).
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| BioInform Feature |
Read the press release announcing an article about our LIMS in Bioinform newsletter. |
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